Gene interactions and pathways from curated databases and text-mining

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KITLG — PTGS2

Text-mined interactions from Literome

Murakami et al., Proc Natl Acad Sci U S A 1995 : Interleukin 4 suppresses c-kit ligand induced expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase 2 and their roles in separate pathways of eicosanoid synthesis in mouse bone marrow derived mast cells
Bingham et al., J Biol Chem 1996 : BALB/cJ mouse bone marrow derived mast cells ( BMMC ) developed with interleukin (IL)-3 can be stimulated by c-kit ligand (KL) in the presence of IL-10 and IL-1beta for sequential immediate and delayed generation of prostaglandin ( PG ) D2 through utilization of constitutive prostaglandin endoperoxide synthase ( PGHS) -1 and induced PGHS-2 , respectively ( Murakami, M., Matsumoto, R., Austen, K. F., and Arm, J. P. ( 1994 ) J. Biol. Chem. 269, 22269-22275 )
Murakami et al., J Immunol 1997 : COX-2 induction and the attendant delayed PGD2 generation in CTMC were modestly induced by c-kit ligand , but not by Fc epsilonRI cross linking