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EPHB2 — MUC2
Text-mined interactions from Literome
Kim et al., J Korean Med Sci 2002
(MAP Kinase Signaling System) :
PD98059 (
MEK/ERK inhibitor )
suppressed IL-1beta mediated MUC2 gene expression and
mucin secretion, while SB203580 ( p38 inhibitor ) did not ... PD98059 (
MEK/ERK inhibitor )
suppressed IL-1beta mediated
MUC2 gene expression and mucin secretion, while SB203580 ( p38 inhibitor ) did not
Alcaide et al., Eur J Immunol 2004
(Chagas Disease) :
Furthermore, AgC10 inhibition must lie upstream in the MAPK activation pathway by LPS, since this
mucin also
inhibited extracellularly regulated kinase (ERK) and Jun kinase (JNK)activation
Yamaguchi et al., Mol Cancer Ther 2008
(Colorectal Neoplasms...) :
Overall, these results indicate that MCC-555 has a potent tumor suppressor activity in intestinal tumorigenesis, likely involving
MUC2 up-regulation by
ERK and PPARgamma pathways
Lim et al., American journal of translational research 2009
:
In the present study, we showed that positive
regulation of MUC5AC
mucin expression by
ERK1/2 is dependent on Ras-Raf-1 signaling pathway, whereas the negative regulation of MUC5AC expression by JNK1/2 is dependent on MEKK3 ...
Ras-Raf1-ERK1/2 dependent AP-1 activation positively
regulates MUC5AC
mucin induction by S. pneumoniae, whereas MEKK3-JNK1/2 dependent AP-1 activation negatively regulates it