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CCR5 — IL6

Text-mined interactions from Literome

Biasin et al., J Infect Dis 2000 : However, interleukin (IL)-6 , IL-10, IL-12, interferon (IFN)-gamma, and tumor necrosis factor (TNF)-alpha and -beta mRNA were elevated in PBMC and cervical mucosa biopsy specimens of ESN and HIV infected women ; CCR5 and CXCR4 mRNA were augmented in cervical mucosa biopsy specimens, but not in PBMC, of ESN and HIV infected women ; HIV-specific IFN-gamma secreting cells were detected in vaginal washes of ESN and HIV infected women ; and phenotypic alterations were present in PBMC of ESN women
Zhang et al., Arthritis Rheum 2005 (Arthritis, Rheumatoid) : In contrast, interleukin-12 stimulation induced the up-regulation of CCR5 and a shift in the in vivo homing pattern away from the lymph nodes toward the inflamed synovium
Abraham et al., Neurobiol Aging 2008 : Cell surface expression of CCR5 was increased by IL-6 in a dose dependent manner
Venza et al., J Periodontol 2010 (Chronic Periodontitis...) : These findings showed that : 1 ) in subjects without diabetes and patients with well controlled diabetes, TNF-alpha, CCR5 , and CXCR3 may constitute distinctive biomarkers of P-IM; 2 ) poor glycemic control abolished the differences between CP and P-IM regarding the expression of these mediators ; and 3 ) type 2 diabetes affected the expression of TNF-alpha, IL-6 and -8, CCR5, and CXCR3
Tang et al., Arthritis Rheum 2010 (Osteoarthritis) : CCL5 mediated IL-6 production was attenuated by CCR5 monoclonal antibody, CCR5 inhibitor ( Met-RANTES ), and CCR5 siRNA ... The present results suggest that the interaction between CCL5 and CCR5 increases IL-6 production in human synovial fibroblasts via the PKCd/c-Src/c-Jun and AP-1 signaling pathways