Gene interactions and pathways from curated databases and text-mining

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PLXNB1 — RASA1

Text-mined interactions from Literome

Oinuma et al., J Neurosci 2004 : Molecular dissection of the semaphorin 4D receptor plexin-B1 stimulated R-Ras GTPase activating protein activity and neurite remodeling in hippocampal neurons ... In this report, critical roles of Rnd1 and Sema4D in Plexin-B1 stimulated R-Ras GAP activity and neurite remodeling were examined
Oinuma et al., J Cell Biol 2006 : Semaphorin 4D/Plexin-B1 mediated R-Ras GAP activity inhibits cell migration by regulating beta ( 1 ) integrin activity ... Thus, we conclude that R-Ras activity is critical for ECM mediated beta ( 1 ) integrin activation and cell migration and that inactivation of R-Ras by Sema4D/Plexin-B1 mediated R-Ras GAP activity controls cell migration by modulating the activity of beta ( 1 ) integrins
Ito et al., EMBO Rep 2006 : Here we characterized the downstream signalling of plexin-B1 mediated R-Ras GAP activity, inducing growth cone collapse
Oinuma et al., J Biol Chem 2010 : Plexin-B1 induced PTEN dephosphorylation through R-Ras GAP activity and R-Ras GAP activity was by itself sufficient for PTEN dephosphorylation and activation
Tasaka et al., J Neurosci 2012 : Semaphorin 4D/Plexin-B1 mediated M-Ras GAP activity regulates actin based dendrite remodeling through Lamellipodin ... In axons, Sema4D stimulation induces growth cone collapse, and downregulation of R-Ras activity by Plexin-B1 mediated GAP activity is required for the action