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PLXNB1 — RASA1
Text-mined interactions from Literome
Oinuma et al., J Neurosci 2004
:
Molecular dissection of the semaphorin 4D receptor
plexin-B1 stimulated R-Ras
GTPase activating protein activity and neurite remodeling in hippocampal neurons ... In this report, critical roles of Rnd1 and Sema4D in
Plexin-B1 stimulated
R-Ras GAP activity and neurite remodeling were examined
Oinuma et al., J Cell Biol 2006
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Semaphorin
4D/Plexin-B1 mediated
R-Ras GAP activity inhibits cell migration by regulating beta ( 1 ) integrin activity ... Thus, we conclude that R-Ras activity is critical for ECM mediated beta ( 1 ) integrin activation and cell migration and that inactivation of R-Ras by
Sema4D/Plexin-B1 mediated
R-Ras GAP activity controls cell migration by modulating the activity of beta ( 1 ) integrins
Ito et al., EMBO Rep 2006
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Here we characterized the downstream signalling of
plexin-B1 mediated
R-Ras GAP activity, inducing growth cone collapse
Oinuma et al., J Biol Chem 2010
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Plexin-B1 induced PTEN dephosphorylation through R-Ras GAP activity and
R-Ras GAP activity was by itself sufficient for PTEN dephosphorylation and activation
Tasaka et al., J Neurosci 2012
:
Semaphorin
4D/Plexin-B1 mediated
M-Ras GAP activity regulates actin based dendrite remodeling through Lamellipodin ... In axons, Sema4D stimulation induces growth cone collapse, and downregulation of R-Ras activity by
Plexin-B1 mediated
GAP activity is required for the action