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IGF1 — MARCKS
Text-mined interactions from Literome
Shiraishi et al., J Cell Physiol 2006
(Neuroblastoma) :
The decrease in
P-MARCKS induced by
IGF-I was blocked by pretreatment of cells with phosphoinositide 3-kinase (PI3K) inhibitors, LY294002 and wortmannin
Yamaguchi et al., J Cell Physiol 2009
(Brain Neoplasms...) :
On the other hand, the phosphoinositide 3-kinase inhibitor, LY294002, abolished
IGF-I induced dephosphorylation, translocation of
MARCKS to lipid rafts, and lamellipodia formation ... Immunocytochemical and immunoprecipitation analysis indicated that
IGF-I stimulation
induced the translocation of
MARCKS to lipid rafts in the edge of lamellipodia and formation of the complex with PIP2