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MYC — PRKACB
Text-mined interactions from Literome
Wu et al., Oncogene 2002
(Cell Transformation, Neoplastic...) :
Here we show that
c-MYC induces the activity of
Protein Kinase A (PKA) , a key effector of cAMP mediated signal transduction, by inducing the transcription of the gene encoding the PKA catalytic subunit beta (PKA-Cbeta) ... c-MYC mediated induction of
PKA-Cbeta gene transcription occurs in multiple tissues, is independent of cell proliferation and is
mediated by direct binding of
c-MYC to the PKA-Cbeta gene promoter sequences
Yu et al., J Mol Med (Berl) 2004
:
Our previous results showed that
c-MYC induces the activity of
PKA by inducing the transcription of the gene encoding the PKA catalytic subunit beta (PKA-Cbeta)