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Ulmann et al., EMBO J 2010
(Inflammation...) :
Stimulating P2X4R in macrophages triggers calcium influx and p38 MAPK phosphorylation, resulting in cytosolic PLA2 (cPLA2) activation and COX dependent release of PGE2
Kawano et al., Biochem Biophys Res Commun 2012
:
In conclusion, our results suggest that P2X4 receptor is involved in P2X7 receptor mediated cell death, but not pore formation or MAPK signaling