◀ Back to PTBP2
PTBP2 — TNFSF4
Text-mined interactions from Literome
Kobayashi et al., Int J Hematol 2004
:
Taken together, our findings show that gp34/
OX40L plays an important role in allogeneic CD4+ T-cell activation by
DCs and that lentiviral gp34/OX40L gene transfer into DCs may be a useful strategy for cancer immunotherapy
Wang et al., Tissue Antigens 2004
:
Furthermore, we demonstrated that our monoclonal antibodies, such as 9H10 and 4C12, could trigger
OX40L reverse signal that enhanced IgG production of B cells and promoted maturation of DCs as evidenced by the upexpression of CD80, CD86, CD83 and CXCR4 and monoclonal antibody 9H10 could also
promote anti-CD40 monoclonal-antibody stimulated
DCs in order to induce T cells to secrete more interleukin-2 and interferon-gamma, which suggested that OX40L signals could strengthen the effect of CD40 signals on promoting Th1 differentiation
Zaini et al., J Clin Invest 2007
(Neoplasms, Experimental) :
These results show a critical
role for
OX40L on
DCs , via binding to OX40 on NKT cells and CD4+ T cells, in the induction of antitumor immunity in tumor bearing mice