Gene interactions and pathways from curated databases and text-mining

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EDN2 — TNF

Text-mined interactions from Literome

Gould et al., Kidney Int 2002 : BMP-7 represses the basal and TNF-alpha stimulated expression of the pro-inflammatory cytokines IL-6 and IL-1beta, the chemokines MCP-1 and IL-8, and the vasoconstrictor ET-2 in PTEC
LaMarca et al., Hypertension 2005 (Hypertension...) : Endothelin is also elevated in preeclampsia and endothelin synthesis is enhanced by TNF-alpha
Lorenz et al., Life Sci 2009 (Vascular Diseases) : TNFalpha induced upregulation of the potent vasoconstrictor endothelin was abolished by MG132
Keiser et al., Am J Hypertens 2009 (Disease Models, Animal...) : We examined the effect of 17-hydroxyprogesterone caproate ( 17-OHP ) on TNF-alpha stimulated endothelin ( ET ) production and hypertension during pregnancy
Redl et al., J Lab Clin Med 1994 (Bacteremia...) : Big-endothelin release in baboon bacteremia is partially TNF dependent
Chanez et al., J Allergy Clin Immunol 1996 (Asthma) : The release of fibronectin and tumor necrosis factor-alpha induced by endothelin was studied in alveolar macrophages by enzyme immunoassay
Kruse-Elliott et al., Shock 1998 : We hypothesized that endothelin ( ET ) may be released in response to tumor necrosis factor-alpha (TNF) and that platelet activating factor (PAF) and cyclooxygenase products modulate TNF induced ET-1 release in vivo
Lambert et al., J Cardiovasc Pharmacol 1998 (Adenocarcinoma...) : Comparison of the regulation of endothelin-2 and endothelin converting enzyme-1 b [ correction of beta ] by forskolin and TNF-alpha in ACHN cells