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IL15 — MICA

Text-mined interactions from Literome

Koning et al., Springer Semin Immunopathol 2005 (Celiac Disease...) : Simultaneously, gluten exposure leads to increased production of IL15 , which induces the expression of NKG2D on intraepithelial lymphocytes and its ligand MICA on epithelial cells, leading to epithelial cell destruction
Molinero et al., Hum Immunol 2006 : Here, we show that IL-2, IL-4, and IL-15 but not TNF-alpha or IFN-alpha induced MICA expression in T lymphocytes present in peripheral blood mononuclear cells ( PBMCs ), as assessed by Western blot
Zhang et al., Cytokine 2008 : NKG2D or MICA blockade attenuated the up-regulation of IL-15 on NK cytolysis, demonstrating that the up-regulatory effect of IL-15 on NK cytolysis is at least partly dependent of the interaction of NKG2D and MICA