Gene interactions and pathways from curated databases and text-mining

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EGF — GRP

Text-mined interactions from Literome

Zhang et al., Cancer Res 2004 (Carcinoma, Squamous Cell...) : In addition to TGF-alpha release, GRP induced amphiregulin, but not EGF , secretion into HNSCC cell culture medium, an effect that was blocked by the MMP inhibitor marimastat
Venkateswarlu et al., Biochem J 1998 : Stimulation with either nerve growth factor or epidermal growth factor ( both at 100 ng/ml ) results in a rapid, PH-domain dependent, translocation of GFP-GRP1 from the cytosol to the plasma membrane, which occurs with a time course that parallels the production of PtdIns ( 3,4,5 ) P3