Gene interactions and pathways from curated databases and text-mining

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EGF — IGFBP1

Text-mined interactions from Literome

Grimes et al., Endocrinology 1992 : However, in the presence of epidermal growth factor ( which was without independent effect on the 30-kDa IGFBP ), insulin also induced this 30-kDa IGFBP
Barreca et al., Mol Cell Endocrinol 1992 : The stimulation of IGF-I and IGFBP secretion by EGF appears to be dose dependent with a significant increment already evident at 5 nM
Angervo et al., J Endocrinol 1992 : These results suggest that EGF regulates IGFBP-1 secretion in human granulosa-luteal cells
Nuttinck et al., Domest Anim Endocrinol 2004 : Under defined culture conditions, IGFBP-2 and FSHR mRNA expression remained at a high level in TCM199 alone and were significantly reduced ( P < 0.05 ) in the presence of 10 ng/ml EGF after a 24 h period of in vitro maturation
Cavaillé et al., Biochem Biophys Res Commun 2006 : IGFBP-1 inhibits EGF mitogenic activity in cultured endometrial stromal cells
Mondschein et al., Endocrinology 1990 : In contrast, IGFBP-3 levels were enhanced by epidermal growth factor
Corps et al., Endocrinology 1991 : Production of this IGFBP by Swiss 3T3 cells was stimulated by 50-150 % by the mitogens bombesin, vasopressin, platelet derived growth factor, epidermal growth factor , and 12-O-tetradecanoylphorbol 13-acetate and also by IGF-I
Murray et al., Endocrinology 1993 : The IGFBP-1 response to EGF was most dramatic in the first few days of life ... Although EGF lowered circulating insulin levels, EGF stimulated IGFBP-1 secretion in the presence of exogenously administered insulin
Oguchi et al., Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1997 : The effects of IGF-I and EGF on IGFBP secretion diminished with increasing cell differentiation