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EGF — HGF

Text-mined interactions from Literome

Grunnet et al., J Hepatol 1999 : In subconfluent culture hepatocyte growth factor increased the DNA synthesis rate 6-fold, epidermal growth factor 3-fold, and insulin-like growth factor-I 2-fold ; that of albumin, urea and glucose was not increased significantly
Wu et al., Growth Horm IGF Res 1998 : Another stable AsA derivative, ascorbic acid 2-phosphate ( AA-2P ) effectively promoted basal and EGF induced HGF secretion by the fibroblasts, but ascorbic acid 2-sulfate ( AA-2S ) was much less effective ... Constitutive and EGF induced HGF gene expression was also up-regulated after adding AsA or AA-2G to the cells
Tfelt-Hansen et al., Endocrinology 2004 (Astrocytoma...) : Although EGF stimulates HGF secretion in U87 cells, the effect of EGF on PTTG mRNA expression is independent of HGF as neutralizing antibody against HGF failed to abolish EGF induced up-regulation of PTTG mRNA
Takami et al., Biochem Biophys Res Commun 2004 : HGF production is induced by the activation of protein kinase A and protein kinase C-mediated pathways, interleukin (IL)-1, tumor necrosis factor (TNF)-alpha, and epidermal growth factor (EGF) in mesenchymal cells ... IL-1alpha, IL-1beta, and TNF-alpha alone had minimal stimulating effects on HGF production in human dermal fibroblasts, but they strongly inhibited production of HGF induced by cholera toxin, 8-bromo-cAMP, EGF , and phorbol 12-myristate 13-acetate ( PMA )
Motoki et al., Biol Pharm Bull 2005 : Tryptanthrin also inhibited HGF production induced by epidermal growth factor (EGF) and platelet derived growth factor
Shirako et al., J Cell Biochem 2008 (Carcinoma, Hepatocellular) : EGF treatment of the cell clones induced strong activation of ERK similar to HGF treatment, but did not inhibit cell proliferation
Matsumoto et al., Biochem Biophys Res Commun 2008 (Carcinoma, Hepatocellular) : Up-regulations of HGF gene expression induced by PMA and EGF were also suppressed by VPA and TSA
Brusevold et al., J Oral Pathol Med 2012 (Carcinoma, Squamous Cell...) : In the E10 cell line, EGF and HGF induced phosphorylation of EGF receptor (EGFR) and Met, respectively, phosphorylation of ERK1/2, p38 and Akt, and dose dependent activation of cell migration
Chang et al., J Cell Mol Med 2012 : It was found that basic fibroblast growth factor, epidermal growth factor and ascorbic acid 2-phosphate promoted HGF secretion in MSCs
Stolz et al., J Cell Biochem 1994 : Taken together, the data suggest that HGF and EGF stimulate divergent as well as redundant signal transduction pathways in the hepatocyte cytoskeleton, and this may result in unique HGF- or EGF-specific motility, morphology, and mitogenicity in hepatocytes
Li et al., J Cell Physiol 1997 : Expression of HGF/SF transcript and protein was up-regulated mildly by epidermal growth factor (EGF) , transforming growth factor-alpha ( TGF-alpha ), or platelet derived growth factor B ( PDGF-BB ) but markedly by interleukin-1 beta (IL-1 beta) and was more pronounced in limbal than in corneal fibroblasts