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GRK1 — IRS1

Text-mined interactions from Literome

Usui et al., Mol Endocrinol 2005 (Insulin Resistance) : Overexpression of KD-GRK2 , but not WT-GRK2, inhibited ET-1 induced serine 612 phosphorylation of IRS-1 and restored activation of this pathway
Ciccarelli et al., Circulation 2011 (Heart Failure...) : This identifies insulin receptor substrate-1 as a novel nonreceptor target for GRK2 and represents a new pathological mechanism for this kinase in the failing heart