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ETS1 — SMAD3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Lindemann et al., J Biol Chem 2001
(Breast Neoplasms) :
In comparison,
Ets1 did not
increase Smad3/TGF beta induced stimulation of the TGF beta-responsive plasminogen activator inhibitor 1 ( PAI-1 ) promoter
Van Beek et al., Arthritis Res Ther 2006
:
Whereas the ability of transfected Ets-1 to activate the CCN2 promoter is dependent on protein kinase C ( PKC ),
Ets-1 in the
presence of co-transfected
Smad3 does not require PKC, suggesting that the presence of Smad3 bypasses the requirement of Ets-1 for PKC to activate target promoter activity
Koinuma et al., Mol Cell Biol 2009
:
We identified novel Smad binding sites in the CDKN1A gene where
Smad2/3 binding was
regulated by
ETS1 and TFAP2A