◀ Back to SETD2

HGF — SETD2

Text-mined interactions from Literome

Tacchini et al., Carcinogenesis 2001 (Carcinoma, Hepatocellular...) : Hepatocyte growth factor (HGF) , a multifunctional cytokine of mesenchymal origin, activates the DNA binding of hypoxia inducible factor-1 (HIF-1) in the HepG2 cell line : the activated complex contained the inducible alpha subunit ... In conclusion, we suggest that HGF triggers a signal transduction cascade involving PI3K and ultimately activates HIF-1
Hara et al., Oral Oncol 2006 (Neoplasm Invasiveness...) : Increased expression of c-Met/hepatocyte growth factor (HGF)-receptor protein in response to hypoxia in thyroid papillary carcinomas is hypoxia-inducible factor-1 (HIF-1) dependent
Lin et al., PloS one 2012 : Moreover, the use of pharmacological inhibitors or genetic inhibition revealed that c-Met, PI3K, Akt, and mTORC1 signaling pathways were potentially required for HGF induced HIF-1a activation