Gene interactions and pathways from curated databases and text-mining

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GNRH1 — PLA2G1B

Text-mined interactions from Literome

Naor et al., Front Neuroendocrinol 2009 (Calcium Signaling...) : The interaction of GnRH with its cognate type I receptor ( GnRHR ) in pituitary gonadotropes results in the activation of Gq/G ( 11 ), phospholipase Cbeta ( PLCbetaI ), PLA(2) , and PLD
Nava et al., Endocrinology 1987 : Therefore, we investigated the role of phospholipase A2 (PLA2) on the release of LHRH from the hypothalamus
Bonney et al., J Reprod Fertil 1993 : Gonadotrophin releasing hormone (GnRH) given to 25-day-old rats ( either untreated or primed with 0.5 mg oestradiol benzoate ) had no effect on ovarian PLA2 activity but the resulting LH surge may have been too transient. ( ABSTRACT TRUNCATED AT 250 WORDS )
Poulin et al., Mol Cell Endocrinol 1996 : This negative feed-back of PKC on GnRH Induced PLC and PLA2 activities was reversed when PKC was either down regulated after long TPA treatments or inhibited by the PKC inhibitors, staurosporine or GF109203X
Poulin et al., Mol Cell Endocrinol 1998 : Interestingly, while the GnRH induced PLA2 activity was rapidly desensitized ( 2.5 min ) after GnRH pretreatments, the neuropeptide evoked PLD activation was affected at later times, indicating an important time dependent contribution of these enzymatic activities in the sequential events underlying the GnRH induced homologous desensitization processes in the gonadotropes