Pathways - manually collected, often from reviews:
BioCarta mechanism of protein import into the nucleus:
NPC complex (RANBP2-NUP214-NUP210-NUP62-NUP153)
→
Cargo/Importin-alpha/Ran/GDP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
(translocation, activates)
BioCarta mechanism of protein import into the nucleus:
RanGAP/RanBP1/RanBP2 complex (RANGAP1-RANBP1-RANBP2)
→
Cargo/Importin-alpha/Ran/GTP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
(modification, activates)
BioCarta mechanism of protein import into the nucleus:
RanGAP/RanBP1/RanBP2 complex (RANGAP1-RANBP1-RANBP2)
→
Cargo/Importin-alpha/Ran/GDP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
(modification, activates)
BioCarta mechanism of protein import into the nucleus:
Cargo/Importin-alpha/Ran/GTP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
→
Cargo/Importin-alpha/Ran/GDP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
(modification, collaborate)
BioCarta mechanism of protein import into the nucleus:
NTF2 (NUTF2)
→
Cargo/Importin-alpha/Ran/GTP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
(modification, collaborate)
BioCarta mechanism of protein import into the nucleus:
Cargo/Importin-alpha/Ran/GTP/Importin-beta complex (KPNA2-RAN-KPNB1)
→
Cargo/Importin-alpha/Ran/GTP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
(modification, collaborate)
BioCarta mechanism of protein import into the nucleus:
Importin-alpha (KPNA2)
→
Cargo/Importin-alpha/Ran/GDP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
(modification, collaborate)
BioCarta mechanism of protein import into the nucleus:
Cargo/Importin-alpha/Ran/GDP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
→
NTF2 (NUTF2)
(modification, collaborate)
BioCarta mechanism of protein import into the nucleus:
Cargo/Importin-alpha/Ran/GDP/Importin-beta/NTF2 complex (KPNA2-RAN-KPNB1-NUTF2)
→
Importin-beta (KPNB1)
(modification, collaborate)