Gene interactions and pathways from curated databases and text-mining

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ITGB1 — MMP7

Text-mined interactions from Literome

Mitra et al., J Environ Pathol Toxicol Oncol 2003 (Melanoma, Experimental...) : RESULTS : The zymographic analysis showed that ligation of cell surface alpha5beta1 integrin by alpha5 monoclonal antibody leads to the expression and activation of MMP-2 and MMP-7 in B16F10 melanoma cells ... CONCLUSION : alpha5beta1 integrin induced expression and activation of MMP-2 and -7 indicates the role of tumor cell surface integrin receptor in the modulation of MMPs and, thereby, the invasive property of tumor cells
Das et al., Life Sci 2008 (Breast Neoplasms) : Blocking of alpha5beta 1 integrin with anti-alpha5 monoclonal antibody inhibits the fibronectin induced MMP activation response appreciably
Huhtala et al., J Cell Biol 1995 : In contrast, peptide V from the heparin binding region, shown previously to stimulate focal contact formation, further enhanced MMP expression by RSF when present on the substrate with 120FN. RSF expressed alpha 4 beta 1 integrin , the receptor for CS-1, and the anti-alpha 4 mAb blocked the ability of CS-1 to suppress MMP induction by 120FN