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ITGB1 — MMP7
Text-mined interactions from Literome
Mitra et al., J Environ Pathol Toxicol Oncol 2003
(Melanoma, Experimental...) :
RESULTS : The zymographic analysis showed that ligation of cell surface
alpha5beta1 integrin by alpha5 monoclonal antibody
leads to the expression and activation of MMP-2 and
MMP-7 in B16F10 melanoma cells ... CONCLUSION :
alpha5beta1 integrin induced expression and activation of
MMP-2 and -7 indicates the role of tumor cell surface integrin receptor in the modulation of MMPs and, thereby, the invasive property of tumor cells
Das et al., Life Sci 2008
(Breast Neoplasms) :
Blocking of
alpha5beta 1 integrin with anti-alpha5 monoclonal antibody
inhibits the fibronectin induced
MMP activation response appreciably
Huhtala et al., J Cell Biol 1995
:
In contrast, peptide V from the heparin binding region, shown previously to stimulate focal contact formation, further
enhanced MMP expression by RSF when present on the substrate with 120FN. RSF expressed
alpha 4 beta 1 integrin , the receptor for CS-1, and the anti-alpha 4 mAb blocked the ability of CS-1 to suppress MMP induction by 120FN