Lin et al., J Biol Chem 2004
(Breast Neoplasms) :
Function neutralizing antibodies to alpha ( v ) beta ( 3 ) and alpha ( v ) beta(5) could inhibit Cyr61 mediated NF-kappaB activation as well as XIAP expression
Lin et al., Clin Cancer Res 2005
(Adenocarcinoma...) :
Function neutralizing antibody to alphavbeta3 but not alphavbeta5 effectively suppressed Cyr61 mediated NF-kappaB activation, COX-2 gene expression, and cell invasiveness