◀ Back to RELA

CYP1A1 — RELA

Pathways - manually collected, often from reviews:

• WikiPathways Aryl Hydrocarbon Receptor: Complex of RELA-NFKB1-PSRC1 → CYP1A1 (inhibition) Ke et al., J Biol Chem 2001*

Text-mined interactions from Literome

Zordoky et al., Curr Drug Metab 2009 (Inflammation) : First, NF-kappaB can directly regulate the expression of CYP1A1 , CYP2B1/2, CYP2C11, CYP2D5, CYP2E1, CYP3A7, and CYP27B1 through binding to the promoter region of these genes
Luecke et al., Chem Biol Interact 2010 : Together, our results suggest that the NFkappaB mediated initial suppression of CYP1A1 as well as the unresponsiveness of AhR signaling to repeated irradiation may be part of a protective cellular UV stress response