UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to VEGFC

SHC1 — VEGFC

Pathways - manually collected, often from reviews:

NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: VEGFR3/VEGFC-D complex (FLT4-FIGF_VEGFC) → SHC/GRB2/SOS1 complex (SOS1-GRB2-SHC1) (modification, activates)
Mäkinen et al., EMBO J 2001, Salameh et al., Blood 2005
Evidence: assay
NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: VEGFR3/VEGFC-D complex (FLT4-FIGF_VEGFC) → SHC/GRB2/SOS1 complex (SOS1-GRB2-SHC1) (modification, activates)
Fournier et al., Oncogene 1995, Fournier et al., J Biol Chem 1996, Fournier et al., Oncogene 1999
Evidence: mutant phenotype, other species