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CDKN1A — CIB1
Text-mined interactions from Literome
Chang et al., Cancer Lett 1999
(Lung Neoplasms) :
Moreover, mimosine
induced p21CIP1 expression in H226 and H358 cells, while it activated
p27KIP1 expression in H322 cells
Bhatia et al., Nutr Cancer 2001
(Carcinoma, Squamous Cell...) :
Quercetin treatment, however, resulted in a moderate
increase in
Cip1/p21 with no change in
Kip1/p27 and a decrease in CDK4 and cyclin D1
Suzuki et al., Hypertens Res 2002
(MAP Kinase Signaling System) :
The results also indicated that the constitutive activation of Ras might have induced the persistent expression of
p21cip1 and p27kip1, and that this induction of p21cip1 and
p27kip1 expression possibly
caused the cell cycle arrest at the G1 phase
Gordon et al., Cancer Chemother Pharmacol 2008
(Mesothelioma...) :
Bortezomib stabilized or
increased protein levels of
p21/WAF1 and IAP-1 and to a lesser degree
p27/KIP1 , IAP-2, XIAP, and survivin
Liu et al., Mol Carcinog 1998
(Carcinoma, Hepatocellular) :
In summary, our results indicated that ( i ) PTDS and DTDS induced apoptosis and G1/S arrest mediated by p53, whereas PDTC, DDTC, and ADTC induced p53 dependent
p21 expression leading to G1/S arrest ; ( ii ) PDTC, DDTC, and ADTC
induced p21/KIP1/CIP1 expression in a p53 dependent pathway leading to G1/S arrest ; and ( iii ) NFkappaB, AP-1, and bcl-2 were downregulated during PTDS- and DTDS induced apoptosis