Brunelli et al., Biochem Pharmacol 2010
(Multiple Myeloma) :
We have evaluated the potency of both compounds in inducing cell death, cell cycle perturbations, apoptosis, NF-kB inhibition and GST-pi activity in human carcinoma cells with different GST-pi contents as well as in human multiple myeloma and leukaemia cell lines
Choi et al., Biochem Pharmacol 1998
:
In contrast, GdCl3, an inhibitor of mEH and GST expression, inhibited LPS induced activation of the p65/p50 NF-kappaB