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IL21 — IRF1

Text-mined interactions from Literome

Coccia et al., J Biol Chem 1999 : No significant differences of IRF-1 mRNA expression were found in established Th1 and Th2 cells ; however, interleukin 12 (IL-12) induced a strong up-regulation of IRF-1 transcripts in Th1 but not in Th2 cells
Biswas et al., J Exp Med 2012 (Autoimmune Diseases...) : In CD4 ( + ) T helper cells, IRF4 plays an essential role in the regulation of IL-21 production, whereas in B cells it controls class switch recombination and plasma cell differentiation