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EFNA1 — IL2
Text-mined interactions from Literome
Wohlfahrt et al., J Immunol 2004
(Asthma) :
Ephrin-A1 engagement
reduced IL-2 expression by 82 % and IL-4 reduced it by 69 % ; the IFN-gamma expression remained unaffected
Freywald et al., J Immunol 2006
(MAP Kinase Signaling System) :
Furthermore,
ephrin-A1 costimulation suppresses up-regulation of both the IL-2R alpha-chain ( CD25 ) and early activation Ag CD69 and can
block IL-2 production by CD4 ( + ) single positive cells ... Furthermore,
ephrin-A1 costimulation suppresses up-regulation of both the IL-2R alpha-chain ( CD25 ) and early activation Ag CD69 and can
block IL-2 production by CD4 ( + ) single positive cells