Gene interactions and pathways from curated databases and text-mining

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GRAP2 — PPARA

Text-mined interactions from Literome

Diradourian et al., Biochim Biophys Acta 2008 (MAP Kinase Signaling System) : In conclusion, we showed that p38 activation induced PPARalpha phosphorylation and inhibition of its transcriptional activity through a trimeric interaction between p38-MAPK, ZIP/p62 and PPARalpha
Lin et al., Cell Signal 2011 (Carcinoma, Non-Small-Cell Lung) : In addition, activation of P(38) instead of ERK played a critical role in TGFß induced expression of PPAR? , which subsequently activated RhoA in H460 cell
Liu et al., Biomaterials 2013 (Brain Ischemia) : Furthermore, CBSA-PEG-TIIA-NPs significantly decreased the mRNA expressions of iNOS and p38MAPK, upregulated PPAR? expression, and inhibited the protein levels of iNOS, GFAP and p38MAPK phosphorylation