Gene interactions and pathways from curated databases and text-mining

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FAS — KRT8

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: Complex of CFLAR-KRT18-KRT8-RAF1 → FAS (increases) Gilbert et al., Mol Cell Biol 2004*
    Evidence: c-Flip, along with Raf-1, is part of a K8/K18-immunoisolated complex from wild-type hepatocytes, and Fas stimulation leads to further c-Flip and Raf-1 recruitment in the complex.