◀ Back to IFI44
IFI44 — LPA
Text-mined interactions from Literome
Estrella et al., Int J Oncol 2007
(MAP Kinase Signaling System...) :
LPA stimulation of ovarian cancer cells markedly
increased the phosphorylation and activity of p38 ( MAPK ),
p42/p44(MAPK) , and PI3K
Hurst et al., BMC neuroscience 2008
:
LPA and S1P also
induce p44/42 ERK MAP kinase phosphorylation in these cells and stimulate cell proliferation via G i/o coupled receptors in an Epidermal Growth Factor Receptor (EGFR)- and ERK dependent pathway
Gaits et al., Kidney Int 1997
(Glomerulonephritis, Membranoproliferative) :
At 10 to 20 microM,
LPA stimulated thymidine incorporation as well as phosphorylation of mitogen activated protein kinases ( MAP-kinases )
p42-p44 in dose- and time dependent manner, which demonstrated a positive effect on cell proliferation