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HDAC3 — SP1

Pathways - manually collected, often from reviews:

• FastForward regulation: SP1 → HDAC3 (transcriptional regulation, unknown)
  Evidence: DNABINDING

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: HDAC3 — SP1 (physical association, affinity chromatography technology) Huang et al., Biochem Biophys Res Commun 2006*

Text-mined interactions from Literome

Sowa et al., Cancer Res 1999 : Sp3, but not Sp1 , mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor
Huang et al., Biochem Biophys Res Commun 2006 : We also showed that HDAC3 repressed GAL4-Sp1 transcriptional activity, and that Sp1 was co-immunoprecipitated with FLAG tagged HDAC3