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CRH — NOS2

Text-mined interactions from Literome

Weidenfeld et al., Neuroendocrinology 1999 : These results suggest that : ( 1 ) NO is involved in modulation of the HPA axis responses to neural stimuli which are not dependent on immune factors, ( 2 ) the effect of NO is mediated by inhibition of hypothalamic ME CRH-41 secretion, and ( 3 ) this effect is probably mediated by neuronal NOS and not by inducible NOS
Cantarella et al., Br J Pharmacol 2001 : Divergent effects of corticotropin releasing hormone on endothelial cell nitric oxide synthase are associated with different expression of CRH type 1 and 2 receptors ... In fact, anti-Svg-30 inhibited CRH induced increase of nitrite release and iNOS expression in HUVEC cells
Karteris et al., J Clin Endocrinol Metab 2005 (Birth Weight...) : In placental explants, CRH and UCN induced mRNA and protein expression of eNOS, but not inducible NOS , and also caused an acute increase in cGMP levels ( maximal stimulation, 80-90 % above basal ; P < 0.05 )
Ralph et al., Am J Pathol 2007 (Arthritis...) : CRH enhanced the expression of nitric-oxide synthase ( NOS III ) to promote NO production from CRH-R1alpha expressing cells
Jain et al., Am J Obstet Gynecol 1997 : The relaxation induced by corticotropin releasing factor in aortic rings from nonpregnant rats decreased after deendothelization and treatment with N omega-nitro-L-arginine methyl ester ( a nitric oxide synthase inhibitor ), LY-83,583 ( a guanylate cyclase inhibitor ), or alpha-helical corticotropin releasing factor 9-41 ( a corticotropin releasing factor antagonist )
Raber et al., Brain research. Brain research reviews 1998 (Disease Models, Animal...) : The IFNalpha stimulated release of AVP and CRH appears to be mediated by cyclic GMP production, and this release by IFNalpha and IL-2 may be mediated in part by activation of constitutive nitric oxide synthase