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FCER2 — IL2
Text-mined interactions from Literome
Yano et al., Nephron 1992
(Glomerulonephritis, IGA...) :
We also examined the
induction of surface
CD23 expression on peripheral lymphocytes by
interleukin (IL)-2 , IL-3, IL-4, IL-5, IL-6, interferon (IFN)-gamma, IFN-alpha, phytohemagglutinin, concanavalin A, pokeweed mitogen, lipopolysaccharide and phorbol myristate acetate
Sugie et al., Proc Natl Acad Sci U S A 1991
(Leukemia, Lymphocytic, Chronic, B-Cell) :
Cross linking of
Fc epsilon RII/CD23 with H107 anti-Fc epsilon RII monoclonal antibody markedly
enhanced interleukin 2 receptor/p55 expression on the YT cells transfected with Fc epsilon RII cDNA ( YTSER cells )
Kawabe et al., J Immunol 1991
:
The induction of
Fc epsilon RII/CD23 on PHA activated T cells was
enhanced by
IL-2 as well as IL-4 ... Both
IL-2 and IL-4 also
augmented PHA induced production of soluble
Fc epsilon RII/CD23 ... The enhanced expression of Fc epsilon RII/CD23 on T cells by both lymphokines was suppressed by rabbit anti-IL-4 antiserum, suggesting the involvement of an IL-4 dependent process even in the
IL-2 dependent
Fc epsilon RII/CD23 expression on T cells
Fischer et al., Immunology 1990
:
Prednisolone suppressed the spontaneous and
IL-2 induced
CD23 expression on PBL of healthy donors
Fischer et al., Int Arch Allergy Appl Immunol 1990
:
It is shown that
IL-2 induced
CD23 expression on human peripheral-blood B cells ... Evidence is presented that the
IL-2 induced
CD23 expression and release of soluble CD23 ( sCD23 ) are not mediated by IL-4 ... In comparison to IL-4, the
IL-2 induced
CD23 expression and sCD23 release revealed kinetic differences and were not inhibited by anti-IL-4 ... Subsequent stimulation with IL-4 induced CD23 to the same extent as on unstimulated cells, whereas the
IL-2 induced
CD23 expression and sCD23 release were greatly reduced ... Interferon gamma showed no effects on the IL-4 stimulated CD23 expression of SAC-PBL, whereas the
IL-2 induced
CD23 expression was suppressed
Hivroz et al., Eur J Immunol 1989
(Leukemia, Lymphocytic, Chronic, B-Cell) :
Regulation by
interleukin 2 of
CD23 expression of leukemic and normal B cells : comparison with interleukin 4 ... Interferon-gamma was able to inhibit this
IL2 mediated up-regulation of
CD23 on normal B cells but not on CLL-B cells ; on those cells interferon-gamma was similarly unable to inhibit the IL4 mediated CD23 up-regulation
Yodoi et al., Ciba Found Symp 1989
:
As indicated by
IL-2 dependent
Fc epsilon RII/CD23 induction, there is an interesting bilateral co-regulation between Fc epsilon RII/CD23 and the 55 kDa chain of the IL-2 receptor complex with Tac antigen ( IL-2R/p55 ( Tac ]
Bourget et al., Eur J Immunol 1995
:
We show that B1 reduced both anti-mu
+ interleukin-4 (IL-4)
induced DNA synthesis and the concomitant expression of
CD23 at the surface of human tonsillar B cells
Gagro et al., Eur J Immunol 1994
(Asthma) :
In this study we investigated the
effect of the Dermatophagoides pteronyssinus (Dpt) allergen and recombinant
interleukin ( rIL ) -4 on the expression of CD21 and
CD23 on T and B cells of asthmatic patients allergic to Dpt and of healthy controls
Carini et al., Int Arch Allergy Immunol 1996
:
The enhanced expression of
CD23 was
blocked by an anti-IL-7 monoclonal antibody ( mAb ), but not by
IL-2 and IL-4 mAbs