Gene interactions and pathways from curated databases and text-mining

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IFNA2 — IL18

Text-mined interactions from Literome

Sissolak et al., Leukemia 1992 (Leukemia, Myeloid, Acute) : Effects of interferon-alpha ( IFN ) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony stimulating factor ( GM-CSF ) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia ( AML ) blasts
Tzung et al., Cancer Immunol Immunother 1991 : Endogenous interferon alpha/beta produced by Kupffer cells inhibits interleukin-1 , tumor necrosis factor alpha production and interleukin-2 induced activation of nonparenchymal liver cells
YingLi et al., Clin Exp Med 2009 (Hepatitis C, Chronic) : PEG-IFN alpha-2a treatment induces a marked decline in IL-18 and remission of hepatic inflammatory in responders at week 24 and week 48 follow-up time point, while increased levels persist in those in whom the HCV infection was not eliminated by the therapy
Gerrard et al., J Immunol 1987 : Differential effects of interferon-alpha and interferon-gamma on interleukin 1 secretion by monocytes
Ohashi et al., J Interferon Res 1994 (Acquired Immunodeficiency Syndrome) : The effects of human interferon-alpha ( IFN-alpha ) on the release of an antimicrobial interleukin , interleukin-8 (IL-8), from human immunodeficiency virus type 1 ( HIV-1 ) -infected myelomonocytic cell line, U937, were studied in vitro to evaluate the potential of IFN-alpha in the management of acquired immunodeficiency syndrome ( AIDS ) -associated opportunistic diseases