◀ Back to JUN

HES1 — JUN

Pathways - manually collected, often from reviews:

• NCI Pathway Database ATF-2 transcription factor network: JUN/ATF2 complex (JUN-ATF2) → HES1 (HES1) (transcription, activates) Sanalkumar et al., J Neurochem 2010*
  Evidence: reporter gene, physical interaction

Text-mined interactions from Literome

Lv et al., Acta Anaesthesiol Scand 2005 : Similarly, HES could inhibit hepatic NF-kappaB and AP-1 activations
Lv et al., Ann Clin Lab Sci 2005 (Sepsis) : HES also down-regulated pulmonary proinflammatory cytokines ( TNF-alpha, IL-1beta, and IL-6 ) and mRNA expressions ( CINC and P-selectin ), and inhibited pulmonary activities of NF-kappaB and AP-1
Lv et al., J Int Med Res 2005 (Endotoxemia...) : HES also decreased the number of MPO positive cells induced by LPS and inhibited activation of NF-kappaB and AP-1
Curry et al., Lab Invest 2006 : Notch independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells
Wang et al., Int Immunopharmacol 2009 (Disease Models, Animal...) : However, HES but not BL could attenuate the increase in MDA level and GSSH/GSH ratio and AP-1 activation