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CDK2 — RPA1

Pathways - manually collected, often from reviews:

• Reactome Reaction: CDK2 → RPA1 (indirect_complex) Zou et al., Mol Cell Biol 2000, Walter et al., Mol Cell 2000
• Reactome Reaction: CDK2 → RPA1 (reaction) Zou et al., Mol Cell Biol 2000, Walter et al., Mol Cell 2000

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: RPA1 — CDK2 (direct interaction, enzymatic study) Pan et al., J Biol Chem 1993
• IRef Biogrid Interaction: RPA1 — CDK2 (direct interaction, enzymatic study) Pan et al., J Biol Chem 1993*
• MIPS CORUM RC complex during S-phase of cell cycle: RC complex during S-phase of cell cycle complex (CCNA2-CDK2-LIG1-PARP1-POLA1-POLD1-POLE-RFC1-RFC2-RPA1-RPA2-RPA3-TOP1) Frouin et al., EMBO J 2002
• IRef Corum Interaction: Complex of 40 proteins (association, anti bait coimmunoprecipitation) Frouin et al., EMBO J 2002

Text-mined interactions from Literome

Zou et al., Mol Cell Biol 2000 : Here we show that both Cdc45p and replication protein A (RPA) bind to Mcm2p at the G ( 1 ) -S transition in an S-CDK dependent manner
Zhu et al., Cell cycle (Georgetown, Tex.) 2005 : In addition, CDK2 inhibition induces an increase in chromatin bound replication protein A (RPA) which should bind to single stranded DNA regions, possibly establishing a replication intermediate that activates the ATR cascade