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E2F1 — TCF23
Text-mined interactions from Literome
Leone et al., Mol Cell 2001
:
Previous work has shown that the Myc
transcription factor induces transcription of the E2F1,
E2F2 , and E2F3 genes ... Previous work has shown that the Myc
transcription factor induces transcription of the
E2F1 , E2F2, and E2F3 genes
Kim et al., Hypertension 2005
(Carotid Artery Injuries) :
In the present study, we examine whether the antiproliferative effect of cilostazol on VSMCs is
mediated by inhibition of an important cell cycle
transcription factor ,
E2F
Hanada et al., Mol Carcinog 2006
:
Also found in breast tumors with high levels is B-Myb, a
transcription factor whose expression is
activated by
E2F1/3 at the late G1 phase and the level is sustained through the S phase
Wang et al., J Biol Chem 2007
:
Here we report that KAP1 binds the E2F1
transcription factor in a retinoblastoma protein ( pRb ) -independent fashion and
inhibits E2F1 activity
Abramova et al., Biochem Biophys Res Commun 2010
:
Here we show that e2f1 expression is regulated through the Wnt/Tcf-pathway :
e2f1 promoter activity is
inhibited by sodium butyrate ( NaB ) and by overexpression of
beta-catenin/Tcf
Xie et al., J Cell Mol Med 2009
:
E2F1 represses
beta-catenin/TCF activity by direct up-regulation of Siah1 ... Moreover,
repression of
beta-catenin/TCF activity by
E2F1 can be attenuated by shRNA based repression of endogenous Siah1, implying that Siah1 is a bona fide E2F1 target gene, which at least partly, mediates the suppression of beta-catenin/TCF signalling pathway
Coleman et al., Journal of oncology 2010
:
T-oligos activated the transcription factor
E2F1 and
inhibited the activity of the angiogenic
transcription factor , HIF-1alpha
Knoll et al., Adv Exp Med Biol 2013
(Disease Progression...) :
MiRs are activated by
E2F1 and either the
transcription factor itself or cellular genes necessary for the growth regulating function of E2F1 are
inhibited by different miRNAs
Defeo-Jones et al., J Virol 1993
(Cell Transformation, Viral...) :
We now show by mutational analysis that the CRPV E7 protein 's biochemical and biological properties, including binding to the retinoblastoma suppressor protein ( pRB ),
transcription factor E2F transactivation of the adenovirus E2 promoter, disruption of pRB-E2F complexes, and cellular transformation as measured by growth in soft agar, mimic those of the HPV E7 protein