Gene interactions and pathways from curated databases and text-mining

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CD46 — IFNG

Text-mined interactions from Literome

Schmitt et al., Eur J Cancer 1999 (Gastrointestinal Neoplasms) : The effects of IFN-gamma on mRNA and protein expression levels of CD46 , CD55 and CD59 were evaluated by Northern blot hybridisation, RT-PCR, flow cytometry and immunostaining
Mason et al., Blood 1999 : Tumor necrosis factor alpha (TNFalpha) and interferon gamma (IFNgamma) each increased DAF expression but not CD59 or MCP expression, and a combination of these cytokines was more potent than either alone
Narumi et al., Cytokine 2000 : On the other hand, JE/MCP-1 mRNA expression was detected only in non-parenchymal cells in response to TNF-alpha and IL-1beta, but not in response to IFN-gamma
Zhou et al., FASEB J 2001 (Astrocytoma) : Regulation of monocyte chemoattractant protein (MCP)-1 transcription by interferon-gamma (IFN-gamma) in human astrocytoma cells : postinduction refractory state of the gene, governed by its upstream elements
Häusler et al., Eur J Neurosci 2002 (Encephalitis...) : While amounts of TNFalpha and IL-6 remained nearly unchanged, IFNgamma enhanced the production of IL-12, MCP-1 and RANTES, but attenuated that of KC, MIP-1alpha and MIP-2
Colotta et al., J Immunol 1992 : IL-1, TNF, IFN-gamma , granulocyte-macrophage-CSF and, to a lesser extent, macrophage-CSF, as well as inactivated streptococci, also induced MCP gene expression
Bosco et al., J Immunol 2004 : Hypoxia also inhibited, in a time dependent fashion, MCP-1 up-regulation by IFN-gamma and LPS
Sánchez et al., Eur J Immunol 2004 : CD46 also enhanced IL-2 or IFN-gamma secretion by CD4+ blasts
Chizzolini et al., Arthritis Res Ther 2006 (Inflammation...) : Thus, Th1 and Th2 cells preferentially induced production of IFN-gamma inducible protein ( IP ) -10 and IL-8, respectively, whereas monocyte chemoattractant protein (MCP)-1 was equally induced by both subsets at mRNA and protein levels
Oliaro et al., Proc Natl Acad Sci U S A 2006 : Ligation of CD46 on human T cells prevented recruitment of the microtubule organizing center, CD3, and perforin to the interface with the antigen presenting cell and caused a reduction in IFN-gamma production
Bordin et al., Int J Oral Maxillofac Implants 2009 (Periodontitis) : Fibroblasts stimulated with TNF alpha showed increased levels of IL6, IL8, MCP1 ; neutrophil chemokine growth related oncogene alpha stimulation with IFN gamma increased MCP1 ; and stimulation with IL4 increased VEGF
Jones et al., J Immunol 2009 : Neither the genetic absence of IL-4, IL-4Ralpha chain, STAT-6, IFN-gamma , or IL-12p40 nor mAb blockade of IFN-gamma, IL-3, IL-4, IL-5, IL-6, IL-10, IL-13, IL-17A, IL-12p40, or IL-12p40Rbeta1 before Ag challenge in WT mice reduces the pulmonary MCp increase
Chensue et al., J Immunol 1996 (Granuloma) : In vivo depletion of IFN-gamma augmented type 2 inflammation and local MCP production ; IL-4 depletion had the opposite effect
Lahrtz et al., Eur J Immunol 1997 (Meningitis, Viral) : To identify the chemotactic signals attracting the cells to the site of infection in the meninges, we measured the levels of two CXC chemokines, interferon-gamma (IFN-gamma) inducible protein (IP)-10 and monokine induced by IFN-gamma , four CC chemokines, monocyte chemotactic protein (MCP)-1 , RANTES, macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta, as well as the cytokines interleukin (IL)-15 and IL-16 in the cerebrospinal fluid (CSF) of patients suffering from viral meningitis