Gene interactions and pathways from curated databases and text-mining

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AHSA1 — PRKAB2

Text-mined interactions from Literome

Xi et al., J Biol Chem 2001 : Moreover, we found that overexpression of the constitutively active form of AMPK mutant also resulted in a significant activation of p38 , and inhibition of p38 activity by SB203580 did not affect AICAR stimulated activation of AMPK ... These findings demonstrate that AICAR stimulated activation of p38 is indeed mediated by AMPK , and the p38 MAPK cascade is downstream of AMPK in the signaling pathway of AICAR stimulated glucose transport in Clone 9 cells
Li et al., Circ Res 2005 (Myocardial Ischemia) : This study examined the role of AMPK in the activation of the p38 mitogen activated protein kinase ( MAPK )
Pan et al., Oncol Rep 2008 (Ovarian Neoplasms) : Our study demonstrated that chemopreventive agent curcumin strongly activates AMPK in a p38 dependent manner in CaOV3 ovarian cancer cells
Choi et al., J Cell Physiol 2013 (Neoplasms) : Furthermore, whereas Compound C ( an AMPK inhibitor ), AMPK-DN ( AMPK-dominant negative ) mutant, and SB203580 ( a p38 MAPK inhibitor ) did not block the 8-Cl-cAMP induced phosphorylation of Akt/PKB, TCN ( an Akt1/2/3 specific inhibitor ) and an Akt2/PKBß targeted siRNA inhibited the 8-Cl-cAMP- and AICAR mediated phosphorylation of AMPK and p38 MAPK