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IDO1 — IL2

Text-mined interactions from Literome

Gordon et al., J Immunol 2005 (Asthma...) : Splenic CD8alpha+ dendritic cells reportedly tolerize T cell responses by inducing Fas ligand mediated apoptosis, suppressing IL-2 expression, or catabolizing T cell tryptophan reserves through expression of IDO
Li et al., Cancer Biol Ther 2009 : We found that IDO produced by IDO stably expressing CHO cells significantly inhibited interleukin (IL)-2 expression and proliferative response in T cells and increased apoptosis of T cells
Carlin et al., J Leukoc Biol 1989 : The induction of IDO activity by IL-2 required both monocytes and lymphocytes ... Interaction was required between these populations for induction of IDO by IL-2 , due to production of IFN-gamma by T lymphocytes, with subsequent IFN-gamma mediated induction of IDO in monocytes