Gene interactions and pathways from curated databases and text-mining

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IL10 — IL23A

Text-mined interactions from Literome

Schuetze et al., Int Immunol 2005 : Whereas p19 was induced early and transiently, p40 and p35 were up-regulated later and then continuously, but the secretion of IL-23 and IL-12p70 was significantly reduced by IL-10
Happel et al., Alcohol Clin Exp Res 2006 (Klebsiella Infections) : The role of IL-10 in alcohol mediated suppression of AM IL-23 p19 mRNA expression was assessed using wild-type ( WT ) and IL-10 knock-out ( KO ) mice
Kim et al., FEMS Immunol Med Microbiol 2007 : Taken together, these data suggest that LTA isolated from L. plantarum elicits stimulatory effects upon the expression of IL-23p19 and inhibitory effects on pathogen mediated IL-10 production
Ong'echa et al., Clin Immunol 2008 (Anemia...) : Since IL-23 and IL-12 share the IL-12p40 subunit and IL-12Rbeta1 receptor, and are down-regulated by IL-10 , relationships among these cytokines were explored in Kenyan children with varying severities of malarial anemia
Albright et al., Immunol Lett 2009 (Colitis) : Recombinant IL-10 suppressed and anti-IL-10 receptor antibody increased IFN-gamma, IL-17 and IL-12/IL-23 p40 production in bacterial lysate pulsed APC and plus CD4 ( + ) T cell co-cultures
Correa et al., Glia 2010 (MAP Kinase Signaling System) : Moreover, endogenously produced IL-10 negatively regulates IL-12 and IL-23 cytokines, which in its turn modify the pattern of expression of transcription factors involved in Th commitment of splenocytes
Li et al., Immunol Cell Biol 2010 (Hepatitis B, Chronic) : Furthermore, endogenous IL-10 inhibited HBcAg stimulated production of IL-17A, IL-22, IL-6 and IL-23 , but not TGF-ß
Zhang et al., Clin Neurol Neurosurg 2010 (Autoimmune Diseases...) : IFNbeta inhibited IL-1beta, IL-23 and transforming growth factor ( TGF ) -beta ( which induce Th17 cell differentiation ), and induced IL-27, IL-12p35 and IL-10 ( which suppress it ) in dendritic cells (DCs) and B-cells
Ahern et al., Immunity 2010 (Colitis) : Furthermore, IL-23R signaling in intestinal T cells suppressed the differentiation of Foxp3 ( + ) cells and T cell IL-10 production
Liu et al., Gastroenterology 2011 (Colitis) : Blocking IL-10 receptors increased production of IFN-? and IL-12/23p40 whereas exogenous IL-10 suppressed these cytokines
Liu et al., J Biol Chem 2012 (Inflammatory Bowel Diseases) : This study aims to elucidate the role of IL-23 in the suppression of IL-10 in the IBD intestinal mucosa
Tian et al., Invest Ophthalmol Vis Sci 2012 (Behcet Syndrome) : VitD3 was able to inhibit the gene expression of RORC, IL-17, IL-23R , CCR6, and Th1 cell differentiation, but upregulated IL-10 expression