Gene interactions and pathways from curated databases and text-mining

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PIK3C3 — PLD1

Text-mined interactions from Literome

Xu et al., J Biol Chem 2011 : Amino acid- and glucose induced PLD and mTORC1 activity were also dependent on the GTPases RalA and ARF6 and the type III phosphatidylinositol-3-kinase hVps34
Yoon et al., J Cell Biol 2011 : Activation of PLD1 by amino acids requires the class III phosphatidylinositol 3-kinase hVps34 , which stimulates PLD1 activity through a functional interaction between phosphatidylinositol 3-phosphate and the Phox homology ( PX ) domain of PLD1