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F2RL3 — PARP1

Text-mined interactions from Literome

Lova et al., J Biol Chem 2004 : We found that, similarly to thrombin, selective stimulation of either PAR-1 or PAR-4 by specific activating peptides caused accumulation of GTP bound Rap1B in a dose dependent manner ... In the presence of the ADP scavengers apyrase or phosphocreatine-phosphocreatine kinase, activation of Rap1B induced by stimulation of either PAR-1 or PAR-4 was totally inhibited ... Concomitant stimulation of both PAR-1 and PAR-4 in the presence of ADP scavengers still resulted in a strongly reduced activation of Rap1B
Cifuni et al., Blood 2008 : Independent roles for CalDAG-GEFI and PKC/Galphai signaling were also observed for PAR4p induced activation of the small GTPase Rap1 , with CalDAG-GEFI mediating the rapid but reversible activation of this small GTPase