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CSF3 — TNF

Text-mined interactions from Literome

Kennedy et al., Exp Hematol 1999 : In the present study the roles of IL-1beta and TNF-alpha in DDTC mediated G-CSF induction were examined using human long-term bone marrow cultures ( hLTBMCs )
Schuld et al., Am J Physiol 1999 : G-CSF did not affect rectal temperature or the plasma levels of cortisol and growth hormone but did induce increases in the plasma levels of IL-1 receptor antagonist and both soluble TNF receptors within 2 h after injection
Zhang et al., J Infect Dis 1999 (Acute Disease...) : G-CSF inhibited MIP-2 but not TNF-alpha production in the lung
Xu et al., Br J Haematol 2000 : In addition to increasing the numbers of neutrophils in vivo and modulating neutrophil functions, G-CSF may induce the production of cytokines such as tumour necrosis factor alpha (TNF-alpha) ... In vitro, G-CSF did not enhance the secretion of TNF-alpha and GM-CSF from mononuclear cells, whole blood or endothelial cells ... However, in the co-presence of whole blood and endothelial cells, the secretion of TNF-alpha was significantly enhanced by G-CSF at low concentrations ... These results together with our previous findings suggest that G-CSF induces the production of TNF-alpha and GM-CSF in vivo, and that this production may be due to the co-effects of endothelial cells and whole blood under the influence of G-CSF through an as yet unknown network of cells and cytokines
Uemura et al., Jpn J Cancer Res 2000 (Carcinoma, Squamous Cell...) : TNF-alpha or IL-1beta induced both G-CSF and PTHrP production in the conditioned medium
Jones et al., Am J Respir Cell Mol Biol 2002 : In addition, IL-17 was found to synergistically enhance TNF-alpha induced production of IL-8, Groalpha, and G-CSF
Boneberg et al., Eur J Immunol 2002 : For TNF-alpha another mechanism of G-CSF action was identified : TNF-alpha as well as proTNF-alpha formation were inhibited by G-CSF , butG-CSF had no influence on LPS induced TNF-alpha mRNA level
Nakata et al., Cancer Sci 2003 (Disease Progression...) : Inflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL)-1beta stimulated the expression of G-CSF , GM-CSF, and cyclooxygenase (COX)-2 in the two cell lines
Sallerfors et al., Eur J Haematol 1992 : In addition to LPS and IL-1, GM-CSF and to a minor degree TNF induced G-CSF secretion
Hareng et al., Eur J Immunol 2003 : Since G-CSF release is mediated , at least in part, by TNF-alpha formation, we investigated whether drugs suppressing TNF-alpha also impair G-CSF production
Kerner et al., Exp Hematol 1992 : Dexamethasone ( 10 ( -5 ) -10 ( -7 ) M ) is able to suppress the tumor necrosis factor (TNF) induced production of granulocyte colony stimulating factor ( G-CSF ) in human umbilical vein endothelial cells ( HUVEC )
Görgen et al., J Immunol 1992 (Drug-Induced Liver Injury...) : The suppressive effect of G-CSF on LPS induced TNF production was also demonstrated in rats ... These data suggest that the G-CSF mediated suppression of TNF production is not a direct effect of G-CSF on macrophages
von Aulock et al., J Pharmacol Exp Ther 2004 : However, flurbiprofen did not affect G-CSF mediated decrease in tumor necrosis factor-alpha or interferon-gamma release
Nishiki et al., Am J Physiol Cell Physiol 2004 (MAP Kinase Signaling System) : G-CSF mediated inhibition of LPS induced TNF-alpha production as well as G-CSF induced STAT3 phosphorylation and suppressor of cytokine signaling 3 mRNA expression were prevented by pretreatment of monocytes with AG-490, an inhibitor of Janus kinase 2 ... These findings suggest that G-CSF , like IL-10, inhibits LPS induced TNF-alpha production in human monocytes through selective activation of STAT3, and the immunomodulation observed in vivo by G-CSF administration may be partly ascribed to the direct effect of G-CSF on monocyte functions
Numasaki et al., Immunol Lett 2004 : While a wide range of doses of IL-17 or IL-17F alone did not up-regulate G-CSF production from primary human LMVECs, IL-17 had an enhancing effect on macrophage derived IL-1beta- and TNF-alpha induced G-CSF production, whereas IL-17F had an enhancing effect on IL-1beta induced production, but an inhibitory effect on TNF-alpha induced secretion ... Moreover, IL-17 plus Th1 or Th2 cytokine had a modest stimulatory effect on TNF-alpha induced G-CSF production, whereas IL-17 plus IFN-gamma had an inhibitory effect on IL-1beta induced release
Miyata et al., Am J Pathol 2006 (Cardiomyopathy, Dilated...) : Granulocyte colony stimulating factor also down-regulated tumor necrosis factor-alpha and increased activities of Akt signal transducer and activator of transcription-3, and matrix metalloproteinases
Kim et al., Cell Microbiol 2006 : By using neutralizing antibodies and G-CSF receptor knockout mice, we demonstrated that G-CSF secreted from L. rhamnosus GG- and GR-1 exposed macrophages suppressed TNF production induced by E. coli- or lipopolysaccharide activated macrophages through a paracrine route
Leizer et al., Blood 1990 : Cytokine regulation of colony stimulating factor production in cultured human synovial fibroblasts : I. Induction of GM-CSF and G-CSF production by interleukin-1 and tumor necrosis factor ... The transcription inhibitor, actinomycin D, and protein synthesis inhibitor, cycloheximide, inhibited the increase in GM-CSF and G-CSF production induced by IL-1 and TNF
Tweardy et al., J Neuroimmunol 1991 (HIV Infections) : In the present study, we examined the effects of TNF-alpha on the production of GM-CSF and G-CSF by U87MG, a human astroglial cell line that constitutively expresses GM-CSF and G-CSF, and U373MG, a second human astroglial cell line that does not produce CSF
Suzuki et al., Int J Hematol 2007 : We also assessed the effect of granulocyte colony stimulating factor ( G-CSF ) pretreatment on TNF-alpha secretion by each cell fraction and found that G-CSF reduced TNF-alpha secretion only in the adherent fraction of cells cultured for 3 weeks
Shieh et al., J Immunol 1991 : In addition, G-CSF binding studies suggested that the TNF induced decrease in G-CSF binding to PEM was probably due to a reduction in receptor number rather than receptor affinity
Ikonomidis et al., Growth Factors 2008 (Breast Neoplasms) : We examined the effects of G-CSF on endothelium, C-reactive protein (CRP), tumour necrosis factor-alpha (TNF-alpha) and anti-inflammatory cytokines namely interleukin 10 (IL-10)
Wang et al., Int J Oncol 1995 : We report that all-trans retinoic acid ( tRA ) synergizes with LPS to enhance the production of granulocyte colony stimulating factor ( G-CSF ) in PMA treated cells, whereas the production of granulocyte-macrophage CSF, interleukin 1-beta (IL-1-beta), and tumor necrosis factor-alpha (TNF-alpha) is minimally affected by tRA
Abe et al., Nihon Rinsho Meneki Gakkai Kaishi 2013 : We also found that high-dose IgG specifically and completely inhibited accelerated expression of KD-related cytokines such as G-CSF , IL-6 and IL-1ß by HCAEC in response to TNF-a
Lee et al., Oncol Rep 2013 : Treatment with U0126 ( a mitogen activated protein kinase inhibitor ) drastically reduced basal levels of G-CSF and TNF-a induced G-CSF in aggressive cancer cells
Caldwell et al., J Cell Physiol 1994 : We further show that IL-1 alpha and TNF alpha synergistically stimulate production of GM-CSF and G-CSF by a clonal stroma derived cell strain
Dunn et al., Blood 1994 : It has previously been shown that a region of the G-CSF promoter, ( -200 to -165 ) containing the decanucleotide CK-1 element and two repeated sequences that resemble nuclear factor (NF)-interleukin-6 (IL-6) binding sites, is required for activation of the G-CSF gene by tumor necrosis factor-alpha (TNF-alpha) and IL-1 beta
Elbaz et al., Leukemia & lymphoma 1994 (Acute Disease...) : TNF , on the other hand, suppresses the G-CSF stimulated AML cell proliferation and serves as a modulator of growth factor receptors on AML cells
Charak et al., Br J Haematol 1994 : TNF- or IFN induced suppression of BM was also inhibited by G-CSF
Kitabayashi et al., Blood 1995 (Burkitt Lymphoma) : G-CSF did not affect the proliferative response of peripheral blood mononuclear cells ( PBMC ) against allogeneic Daudi cells but did inhibit tumor necrosis factor (TNF)-alpha secretion ... G-CSF mediated suppression of TNF-alpha production was not affected by fixation of stimulators ... G-CSF did not inhibit TNF-alpha mRNA expression or accelerate mRNA degradation, whereas pentoxifylline inhibited the expression of TNF-alpha mRNA
Caldwell et al., Blood 1995 : Taken together, these results raise the possibility that IL-1 alpha cross-induction of TNF receptors may contribute to the biochemical mechanisms underlying the synergistic stimulation of G-CSF and GM-CSF production by IL-1 alpha and TNF alpha
Aman et al., Blood 1994 : Production of granulocyte-macrophage colony stimulating factor ( GM-CSF ), granulocyte-CSF (G-CSF) , and interleukin-1 beta (IL-1 beta) in stromal cell layers was induced by incubation with IL-1 alpha, tumor necrosis factor (TNF) , or lipopolysaccharide (LPS)
Futenma et al., Microbiol Immunol 1995 (Agranulocytosis...) : G-CSF significantly prolonged the survival time of granulocytopenic mice, promoted the clearance of organisms through increasing the counts of PMN in the lung, and strongly inhibited the production of TNF-alpha both in BALF and serum
Pollmächer et al., Blood 1996 (Fever...) : G-CSF itself increased granulocyte and monocyte counts and the plasma levels of tumor necrosis factor-alpha (TNF-alpha) , soluble TNF receptors ( sTNF-R ) p55, and p75 and interleukin-1 receptor antagonist ( IL-1ra )
Lundblad et al., Crit Care Med 1996 (Cecal Diseases...) : Granulocyte colony stimulating factor improves survival rate and reduces concentrations of bacteria, endotoxin, tumor necrosis factor , and endothelin-1 in fulminant intra-abdominal sepsis in rats ... G-CSF attenuated the sepsis induced enhancement of circulating bacteria, endotoxin, TNF , and endothelin-1, resulting in improved fluid balance and reduced lactate concentration
Vandermolen et al., J Soc Gynecol Investig 1996 : Each cytokine induced G-CSF protein production in dose-and time dependent manners, with IL-1 beta more potent than TNF-alpha ... Interleukin-1 beta and TNF-alpha stimulate G-CSF production by placental villous core mesenchymal cells in vitro
Pajkrt et al., Blood 1997 (Endotoxemia) : In group 1, G-CSF significantly enhanced the release of tumor necrosis factor (TNF) , interleukin-6 (IL-6), IL-8, IL-1 receptor antagonist (IL-1ra), and soluble TNF receptors ... In group 2, G-CSF significantly reduced IL-8 concentrations and modestly attenuated TNF and IL-6 levels
Koyama et al., Am J Physiol 1998 : The release of G-CSF in response to TNF-alpha , LPS, and BK was significantly increased