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ADCY4 — GPR3
Text-mined interactions from Literome
Li et al., J Biol Chem 2010
:
Mechanistic investigations have shown that as a G ( i ) -coupled receptor,
GPR109A inhibits
adenylate cyclase activity upon niacin activation, thereby inhibiting free fatty acid liberation
Li et al., J Biol Chem 2011
:
Mechanistic investigations have shown that, upon niacin activation,
GPR109A couples to a G(i) protein and
inhibits adenylate cyclase activity, leading to inhibition of liberation of free fatty acid
Zhang et al., J Zhejiang Univ Sci B 2012
:
Expression of porcine
Gpr3 in HEK293 cells
resulted in constitutive activation of
adenylate cyclase ( AC ) similar in amplitude to that produced by fully stimulated G ( s ) -coupled receptors
Jalink et al., Cell Growth Differ 1993
:
LPA stimulates phospholipase C and
inhibits adenylate cyclase in its target cells, apparently by activating a specific
G-protein coupled receptor