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IL13 — PLA2G4A

Text-mined interactions from Literome

Rey et al., Biochim Biophys Acta 1999 : IL-13 induces serine phosphorylation of cPLA2 in mouse peritoneal macrophages leading to arachidonic acid and PGE2 production and blocks the zymosan induced serine phosphorylation of cPLA2 and eicosanoid production ... Conversely, in macrophages stimulated by zymosan, IL-13 added 30 min before zymosan inhibited the AA release and the serine phosphorylation of cPLA2 induced by the phagocytic agonist
Lefebvre et al., FASEB J 2010 : As negative controls, interleukin-8- and formyl-methionyl-leucyl-phenylalanine elicited migration in vitro was not inhibited either by an LTB ( 4 ) receptor antagonist or by the cPLA(2)alpha inhibitor
Chi et al., Arthritis Rheum 2011 (Arthritis, Rheumatoid) : Cytosolic phospholipase A2 induction and prostaglandin E2 release by interleukin-1ß via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-?B activity in human rheumatoid arthritis synovial fibroblasts
Onoe et al., J Immunol 1996 (Bone Resorption) : A small increase ( 1.7-fold ) in cPLA2 mRNA levels was detected in the cultures with IL-1 alpha, but the expression was not affected by IL-13 or IL-4
Rey et al., Biochim Biophys Acta 1998 (Inflammation) : Indeed, IL-13 induces a time dependent increase in the levels of cytosolic PLA2 (cPLA2) protein and mRNA