Gene interactions and pathways from curated databases and text-mining

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RAC1 — TIMP2

Text-mined interactions from Literome

Zhuge et al., J Biol Chem 2001 (Carcinoma, Squamous Cell...) : However, TIMP-2 expression was independent of Rac1 activity
Engers et al., J Biol Chem 2001 (Carcinoma, Renal Cell...) : Indeed, Tiam1 mediated Rac activation induced transcriptional up-regulation of tissue inhibitor of metalloproteinases-1 ( TIMP-1 ) and post-transcriptional up-regulation of TIMP-2 , whereas secretion and activity levels of their counterparts, matrix metalloproteinase-9 and matrix metalloproteinase-2, respectively, were not affected