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CXCL9 — IL1B
Text-mined interactions from Literome
Sauty et al., J Immunol 1999
:
We found that IFN-gamma, but not TNF-alpha or
IL-1 beta , strongly
induced IP-10,
Mig , and I-TAC mRNA accumulation mainly in NHBEC and that TNF-alpha and IL-1 beta synergized with IFN-gamma induction in all three cell types
Mignon et al., Am J Respir Crit Care Med 1999
(Disease Models, Animal...) :
However,
YVAD-CMK does not
affect LPS induced release of
IL-1beta and does not protect from a lethal dose of LPS in unsensitized mice
Cheng et al., J Immunol 2002
:
The eotaxin/CCL11-suppressive effect on endothelial cells was not seen on
IL-1beta induced
IL-8/CXCL8 release
Méndez-Samperio et al., J Interferon Cytokine Res 2002
:
In addition, the specificity of this inhibition was demonstrated by the inability of herbimycin-A to block in a significant manner
IL-1 beta induction of
CXCL-8
McLoughlin et al., J Immunol 2004
(Peritonitis) :
Moreover, when complexed with IL-6, both isoforms specifically inhibited the
IL-1 beta induced secretion of
CXCL8
Dajotoy et al., J Leukoc Biol 2004
(Crohn Disease) :
TNF-alpha but not
IL-1beta enhanced the IFN-gamma induced production of
MIG and IP-10
Dragon et al., Am J Physiol Lung Cell Mol Physiol 2007
:
IL-17 enhances
IL-1beta mediated
CXCL-8 release from human airway smooth muscle cells ... In this study, we evaluated whether IL-17 could enhance
IL-1beta mediated
CXCL-8 release from human airway smooth muscle cells ( HASMC ) and investigated the upstream and downstream signaling events regulating the induction of CXCL-8
Gemma et al., Eur J Neurosci 2007
:
Here we analysed cells positive for 5-bromo-2-deoxyuridine ( BrdU ; 50 mg/kg ) in animals in which cleavage of
IL-1beta was
inhibited by the caspase-1 inhibitor
Ac-YVAD-CMK ( 10 pmol )
Johnston et al., Br J Dermatol 2008
(Chronic Disease...) :
In vitro, both leptin and resistin could induce
CXCL8 and tumour necrosis factor-alpha production by blood monocytes, and leptin could additionally
induce IL-1beta and IL-1 receptor antagonist production
Charron et al., J Biol Chem 2009
(Inflammation) :
Hypoxia enhanced
interleukin-1beta induced interleukin-8 (
CXCL8 ) production in A549 cells and decreased the ability of dexamethasone to suppress the CXCL8 production
Sunil et al., Int J Colorectal Dis 2010
:
Influence of NFkappaB inhibitors on
IL-1beta induced chemokine
CXCL8 and -10 expression levels in intestinal epithelial cell lines : glucocorticoid ineffectiveness and paradoxical effect of PDTC ...
Il-1beta stimulated
CXCL8 and CXCL10 mRNA and protein expression and was studied in Caco-2 and HT29 cells in the presence and absence of the NFkappaB inhibitors by quantitative real-time polymerase chain reaction and enzyme linked immunosorbent serologic assay, respectively
Marotte et al., Rheumatology (Oxford) 2010
(Arthritis, Experimental...) :
GTE ( 2.5-40 microg/ml ) inhibited
IL-1beta induced MCP-1/CCL2 ( 10 ng/ml ), RANTES/CCL5, GROalpha/CXCL1 and
IL-8/CXCL8 production in human RA synovial fibroblasts ( P < 0.05 )
Olaru et al., J Invest Dermatol 2010
(Staphylococcal Skin Infections) :
IL-1alpha and
IL-1beta increased mRNA production and protein secretion of the neutrophil chemotactic CXCL1,
CXCL2 , and IL-8 in keratinocytes
Földes et al., PloS one 2010
:
Expression of downstream TLR signalling pathways was demonstrated in hESC, and
IL-1beta , TNFalpha and INFgamma, which bypass the TLRs,
stimulated CXCL8 release