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EPHB2 — PDGFC

Text-mined interactions from Literome

Midgley et al., J Biol Chem 2004 : Fibroblast growth factor-2 induction of platelet derived growth factor-C chain transcription in vascular smooth muscle cells is ERK dependent but not JNK dependent and mediated by Egr-1 ... Moreover, using pharmacological inhibitors we demonstrate the critical role of ERK but not JNK in FGF-2-inducible PDGF-C expression ... These findings thus demonstrate that PDGF-C transcription, activated by FGF-2, is mediated by Egr-1 and its upstream kinase ERK
Gebhard et al., Basic Res Cardiol 2010 : PD98059, a specific inhibitor of ERK phosphorylation, but not the p38 inhibitor SB203580 or the JNK inhibitor SP600125 prevented PDGF-CC induced TF expression in a concentration dependent manner ... PDGF receptor alpha and PDGF receptor beta inhibition prevented PDGF-CC induced ERK phosphorylation
Seikrit et al., Nephrol Dial Transplant 2013 : Both PDGF-AA and PDGF-CC induced phosphorylation and activation of extracellular signal regulated kinase 1 ( ERK1 ) and ERK2