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GAS6 — MAPK7

Text-mined interactions from Literome

Goruppi et al., Oncogene 1999 : We further show evidence that Gas6 stimulation of serum starved NIH3T3 cells results in a transient ERK, JNK/SAPK and p38 MAPK activation
Katagiri et al., J Biol Chem 2001 (Bone Resorption) : Gas6 up-regulated the phosphorylation of cellular proteins including p42/p44 mitogen activated protein kinase ( MAPK ), but not p38 or c-Jun N-terminal kinase MAPK , and increased the kinase activity of immunoprecipitated Tyro 3 in isolated osteoclasts ... These results strongly suggest that Gas6 acts directly on mature osteoclasts through activation of Tyro 3 and p42/p44 MAPK , possibly contributing to the bone loss by estrogen deficiency
Motomura et al., Biochem Biophys Res Commun 2007 : Gas6 signaling activated the phosphorylation of ERK1/2, SAPK/JNK, and Akt, but not p38 MAPK
Lee et al., Biochem Biophys Res Commun 2013 (MAP Kinase Signaling System...) : Gas6 induces cancer cell migration and epithelial-mesenchymal transition through upregulation of MAPK and Slug