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IL17D — PIM1
Text-mined interactions from Literome
Owaki et al., J Immunol 2008
:
In contrast,
IL-27 augmented c-Myc and
Pim-1 expression and induced cell proliferation in wild-type naive CD4+ T cells but not in STAT3-deficient cohorts
Charlot-Rabiega et al., J Biol Chem 2011
:
IL-27 proliferative effect on naive CD4 ( + ) T cells is independent of MAPK, but is dependent on c-Myc and
Pim-1 induction by
IL-27 and is associated with induction of cyclin D2, cyclin D3, and CDK4 by IL-27 in a c-Myc and Pim-1 dependent manner ... In BCR stimulated naive B cells,
IL-27 only increases entry in the S phase and
induces the expression of
Pim-1 and of cyclins A, D2, and D3